ICU-metabolism.se © 2010 

Nicolas Tardif

Postdoc

Me: I am born in 1982 in Cognac, France. After a bachelor in metabolic biochemistry obtained in La Rochelle, I moved to Clermont-Ferrand in order to study human nutrition. After completing my Master in Human nutrition, I got my PhD in 2011. In 2012, I joined the group as a postdoc fellow to complete my expertise in the field of skeletal muscle metabolism.

My research: Since my PhD I work on the mechanisms leading to the skeletal muscle loss. My PhD investigated the deregulation of skeletal muscle protein synthesis induce by the combined effects of aging and obesity, sarcopenic obesity. In our group I have started by working on the proteolytic pathways responsible of the muscle loss in cancer patients, phenomenon called cachexia. I am currently working on the involvement of one of these proteolytic pathways, autophagic-lysosomal system, in the development of organ failure in the intensive care patients. My field of expertise concerns the biochemistry techniques and the cell biology. Since my arrival I have notably established the western-blot activity within the lab and started the skeletal muscle culture in vitro.